The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2020
Filed:
Jan. 15, 2016
Ionis Pharmaceuticals, Inc., Carlsbad, CA (US);
Fred Hutchinson Cancer Research Center, Seattle, WA (US);
Frank Rigo, Carlsbad, CA (US);
Stephen J. Tapscott, Seattle, WA (US);
Ionis Pharmaceuticals, Inc., Carlsbad, CA (US);
Fred Hutchinson Cancer Research Center, Seattle, WA (US);
Abstract
The present disclosure pertains generally to double-stranded small interfering RNAs that modulate gene expression for use in research, diagnostics, and/or therapeutics. In certain embodiments, the present disclosure provides double-stranded small interfering RNAs that modulate DUX4 gene expression. In certain embodiments, the present disclosure provides methods of inhibiting DUX4 gene expression by contacting a cell with double-stranded small interfering RNAs.