The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2020
Filed:
Nov. 30, 2016
Applicant:
Histogen, Inc., San Diego, CA (US);
Inventors:
Gail K. Naughton, Encinitas, CA (US);
Francis C. Zeigler, Encinitas, CA (US);
Mark Baumgartner, San Diego, CA (US);
Kyle Nickey, Vista, CA (US);
Assignee:
Histogen, Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); A61L 27/22 (2006.01); A61L 27/38 (2006.01); C07K 14/47 (2006.01); C12N 5/071 (2010.01); C12N 5/077 (2010.01); C12N 5/0775 (2010.01); A61K 8/98 (2006.01); A61K 35/33 (2015.01); A61Q 19/08 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0075 (2013.01); A61K 8/981 (2013.01); A61K 35/33 (2013.01); A61L 27/227 (2013.01); A61L 27/3834 (2013.01); A61L 27/3895 (2013.01); A61Q 19/08 (2013.01); C07K 14/47 (2013.01); C12N 5/0068 (2013.01); C12N 5/0627 (2013.01); C12N 5/0656 (2013.01); C12N 5/0662 (2013.01); A61K 38/00 (2013.01); C12N 2500/02 (2013.01); C12N 2500/90 (2013.01); C12N 2533/90 (2013.01);
Abstract
The present invention is directed to a method of producing compositions including embryonic proteins. The method includes culturing cells under hypoxic conditions on a biocompatible surface in vitro. The culturing method produces both soluble and non-soluble fractions, which may be used separately or in combination to obtain physiologically acceptable compositions useful in a variety of medical and therapeutic applications.