The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2020

Filed:

Apr. 29, 2019
Applicant:

Vanderbilt University, Nashville, TN (US);

Inventors:

John P. Wikswo, Brentwood, TN (US);

Ronald S. Reiserer, Nashville, TN (US);

Kyle Hawkins, Nashville, TN (US);

Assignee:

VANDERBILT UNIVERSITY, Nashville, TN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12M 3/06 (2006.01); C12M 1/36 (2006.01); F04B 43/00 (2006.01); B01L 3/00 (2006.01); A01N 1/02 (2006.01); C12M 3/00 (2006.01); C12M 1/32 (2006.01); C12M 1/00 (2006.01); C12M 1/34 (2006.01); F04B 19/00 (2006.01); C12M 1/12 (2006.01); F04B 43/12 (2006.01);
U.S. Cl.
CPC ...
C12M 23/16 (2013.01); A01N 1/0247 (2013.01); B01L 3/5027 (2013.01); C12M 23/12 (2013.01); C12M 23/44 (2013.01); C12M 23/58 (2013.01); C12M 25/02 (2013.01); C12M 29/00 (2013.01); C12M 29/10 (2013.01); C12M 41/36 (2013.01); C12M 41/48 (2013.01); F04B 19/006 (2013.01); F04B 43/0045 (2013.01); F04B 43/12 (2013.01); B01L 3/502715 (2013.01);
Abstract

A system for microdialysis imaging and regional fluidic delivery and control includes a microdialysis imager including a imaging head having N pixels aligned in a pixel array for monitoring a living bio-object associated with the pixel array; and a fluidic module coupled to the microdialysis imager for delivering a fluidic substance to and collecting effluent from the living bio-object, including a fluidic network having a plurality of valves, a plurality of fluidic channels in fluidic communication with the plurality of valves and one or more pumps coupled to corresponding fluidic channels, and a microcontroller coupled to the fluidic network for individually controlling the plurality of valves and the one or more pumps of the fluidic network as so to operably and selectively deliver the fluidic substance to and continuously collect the effluent from the living bio-object responsive to the delivered fluidic substance via each pixel in real time.


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