The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2020

Filed:

Apr. 06, 2016
Applicant:

Centrillion Technology Holdings Corporation, Grand Cayman, KY;

Inventors:

Wei Zhou, Saratoga, CA (US);

Jeremy Edwards, Albuquerque, NM (US);

Justin Costa, Union City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6804 (2018.01); C12N 15/10 (2006.01); C12Q 1/6811 (2018.01); C12Q 1/6874 (2018.01); C07K 16/44 (2006.01); C07K 16/46 (2006.01);
U.S. Cl.
CPC ...
C07K 16/44 (2013.01); C07K 16/46 (2013.01); C12N 15/1006 (2013.01); C12N 15/1065 (2013.01); C12N 15/1093 (2013.01); C12Q 1/6804 (2013.01); C12Q 1/6811 (2013.01); C07K 2317/92 (2013.01); C07K 2319/01 (2013.01); C07K 2319/20 (2013.01); C12Q 1/6874 (2013.01); C12Q 2523/303 (2013.01); C12Q 2535/122 (2013.01); C12Q 2537/164 (2013.01); C12Q 2565/501 (2013.01); C12Q 2600/156 (2013.01);
Abstract

Provided herein are methods and compositions for analyzing epigenetic modifications of genomes. The methods and compositions are suited for complete epigenome sequencing of any modification for which an antibody or an affinity binding agent has been developed. In one aspect, provided herein is a method for analyzing epigenetic modification of a genome. In some embodiments of aspects provided herein, the method further comprises sequencing a sequencing library to generate sequence reads, and assembling the sequence reads with aid of a positional barcode sequence information. In some embodiments of aspects provided herein, the method further comprises determining a location of at least two different epigenetic modifications of the nucleic acid. Another aspect of the present disclosure provides a kit for analyzing an epigenetic modification of a nucleic acid.


Find Patent Forward Citations

Loading…