The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2020
Filed:
Jul. 30, 2015
Applicant:
Fred Hutchinson Cancer Research Center, Seattle, WA (US);
Inventors:
Thomas M. Schmitt, Seattle, WA (US);
Philip D. Greenberg, Mercer Island, WA (US);
Hieu Nguyen, Federal Way, WA (US);
Assignee:
FRED HUTCHINSON CANCER RESEARCH CENTER, Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/00 (2006.01); C07K 14/00 (2006.01); C07K 16/30 (2006.01); C07K 14/725 (2006.01); A61K 35/17 (2015.01); A61K 38/17 (2006.01); A61K 38/20 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/7051 (2013.01); A61K 35/17 (2013.01); A61K 38/1774 (2013.01); A61K 38/2013 (2013.01); A61K 38/2086 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); C07K 2319/00 (2013.01);
Abstract
The present disclosure provides high affinity and enhanced affinity T cell receptors specific for human Wilms tumor protein 1 (WT-1) epitopes for use in treating diseases or disorders, such as cancer cells that overexpress WT-1.