The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2020
Filed:
Sep. 11, 2014
Bristol-myers Squibb Company, Princeton, NJ (US);
Michael Matthew Miller, Lambertville, NJ (US);
Claudio Mapelli, Langhorne, PA (US);
Martin Patrick Allen, Flemington, NJ (US);
Michael S. Bowsher, Prospect, CT (US);
Eric P. Gillis, Cheshire, CT (US);
David R. Langley, Meriden, CT (US);
Eric Mull, Guilford, CT (US);
Maude A. Poirier, Pennington, NJ (US);
Nishith Sanghvi, Bridgewater, NJ (US);
Li-Qiang Sun, Glastonbury, CT (US);
Daniel J. Tenney, Yardley, PA (US);
Kap-Sun Yeung, Madison, CT (US);
Juliang Zhu, North Haven, CT (US);
Kevin W. Gillman, Madison, CT (US);
Qian Zhao, Wallingford, CT (US);
Katharine A. Grant-Young, Madison, CT (US);
Paul Michael Scola, Glastonbury, CT (US);
Lyndon A. M. Cornelius, Jackson, NJ (US);
BRISTOL-MYERS SQUIBB COMPANY, Princeton, NJ (US);
Abstract
The present disclosure provides novel macrocyclic peptides which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.