The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2020

Filed:

Feb. 15, 2019
Applicant:

Oncoarendi Therapeutics S.a., Warsaw, PL;

Inventors:

Marzena Mazur, Lodz, PL;

Robert Koralewski, Lodz, PL;

Bartlomiej Borek, Lodz, PL;

Sylwia Olejniczak, Lodz, PL;

Wojciech J. Czestkowski, Pabianice, PL;

Michal C. Piotrowicz, Lodz, PL;

Jacek P. Olczak, Lodz, PL;

Adam A. Golebiowski, Madison, CT (US);

Agnieszka Bartoszewicz, Warsaw, PL;

Elzbieta Maziarz, Kamien, PL;

Michal L. Kowalski, Godziszka, PL;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); C07D 401/14 (2006.01); C07D 487/04 (2006.01); C07D 413/14 (2006.01); C07D 498/04 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/5377 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 487/04 (2013.01); C07D 498/04 (2013.01);
Abstract

Disclosed are amino triazole compounds substituted with a piperidinyl ring that is itself substituted with a heterocyclic ring. These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.


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