The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2020

Filed:

Jul. 27, 2016
Applicant:

Chong Kun Dang Pharmaceutical Corp., Seoul, KR;

Inventors:

Jaekwang Lee, Gyeonggi-do, KR;

Younghue Han, Gyeonggi-do, KR;

Yuntae Kim, Gyeonggi-do, KR;

Daekyu Choi, Gyeonggi-do, KR;

Jaeki Min, Gyeonggi-do, KR;

Miseon Bae, Gyeonggi-do, KR;

Hyunmo Yang, Gyeonggi-do, KR;

Dohoon Kim, Gyeonggi-do, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 271/10 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 413/04 (2006.01); C07D 417/12 (2006.01); C07D 513/04 (2006.01); A61P 25/00 (2006.01); A61P 35/00 (2006.01); A61P 37/00 (2006.01);
U.S. Cl.
CPC ...
C07D 271/10 (2013.01); A61P 25/00 (2018.01); A61P 35/00 (2018.01); A61P 37/00 (2018.01); C07D 413/04 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); C07D 513/04 (2013.01);
Abstract

The present invention relates to novel compounds represented by the formula I having histone deacetylase 6 (HDAC6) inhibitory activity, stereoisomers thereof or pharmaceutically acceptable salts thereof, the use thereof for the preparation of therapeutic medicaments, pharmaceutical compositions containing the same, a method for treating diseases using the composition, and methods for preparing the novel compounds. (I) The novel compounds, stereoisomers thereof or pharmaceutically acceptable salts thereof according to the present invention have histone deacetylase (HDAC) inhibitory activity and are effective for the prevention or treatment of HDAC6-mediated diseases.


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