The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2020
Filed:
Feb. 16, 2016
Applicants:
The University of Queensland, Queensland, AU;
The Provost, Fellows, Foundation Scholars, and the Other Members of the Board of the College of the Holy and Undivided Trinity of Queen Elizabeth Near Dublin, Dublin, IE;
Inventors:
Luke O'Neill, Dublin, IE;
Rebecca Coll, West End, AU;
Matthew Cooper, Chapel Hill, AU;
Avril Robertson, Kenmore, AU;
Kate Schroder, Fairfield, AU;
Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 311/56 (2006.01); C07D 307/18 (2006.01); C07D 307/64 (2006.01); C07D 407/12 (2006.01); C07D 493/04 (2006.01); C07D 405/12 (2006.01); C07D 333/34 (2006.01); C07D 277/36 (2006.01); C07D 249/12 (2006.01); C07D 249/04 (2006.01); C07D 231/18 (2006.01); C07D 403/12 (2006.01); C07C 311/60 (2006.01); C07D 333/52 (2006.01); C07D 249/06 (2006.01); C07D 413/12 (2006.01); C07D 495/04 (2006.01); C07D 401/12 (2006.01); C07D 241/24 (2006.01); C07D 307/68 (2006.01); C07D 271/12 (2006.01); C07D 311/16 (2006.01); C07D 317/62 (2006.01); C07D 487/04 (2006.01); C07D 215/36 (2006.01); C07D 217/02 (2006.01); C07D 241/42 (2006.01); C07D 498/04 (2006.01); C07D 307/82 (2006.01); C07D 333/62 (2006.01); C07D 217/24 (2006.01); C07D 207/38 (2006.01); C07D 261/18 (2006.01); C07D 213/71 (2006.01); C07D 221/18 (2006.01); C07D 309/08 (2006.01); A61P 1/00 (2006.01); C07D 417/12 (2006.01); C07D 495/06 (2006.01); C07D 311/60 (2006.01); A61P 35/00 (2006.01); A61P 3/00 (2006.01); C07D 235/02 (2006.01); C07D 311/18 (2006.01); A61P 17/00 (2006.01); A61P 5/00 (2006.01); C07D 401/06 (2006.01); A61P 37/00 (2006.01); A61P 25/00 (2006.01); C07D 217/22 (2006.01); C07D 241/44 (2006.01);
U.S. Cl.
CPC ...
C07C 311/56 (2013.01); A61P 1/00 (2018.01); A61P 3/00 (2018.01); A61P 5/00 (2018.01); A61P 17/00 (2018.01); A61P 25/00 (2018.01); A61P 35/00 (2018.01); A61P 37/00 (2018.01); C07C 311/60 (2013.01); C07D 207/38 (2013.01); C07D 213/71 (2013.01); C07D 215/36 (2013.01); C07D 217/02 (2013.01); C07D 217/22 (2013.01); C07D 217/24 (2013.01); C07D 221/18 (2013.01); C07D 231/18 (2013.01); C07D 235/02 (2013.01); C07D 241/42 (2013.01); C07D 241/44 (2013.01); C07D 249/04 (2013.01); C07D 249/06 (2013.01); C07D 249/12 (2013.01); C07D 261/18 (2013.01); C07D 271/12 (2013.01); C07D 277/36 (2013.01); C07D 307/18 (2013.01); C07D 307/64 (2013.01); C07D 307/68 (2013.01); C07D 307/82 (2013.01); C07D 309/08 (2013.01); C07D 311/16 (2013.01); C07D 311/18 (2013.01); C07D 311/60 (2013.01); C07D 317/62 (2013.01); C07D 333/34 (2013.01); C07D 333/52 (2013.01); C07D 333/62 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 407/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 487/04 (2013.01); C07D 493/04 (2013.01); C07D 495/04 (2013.01); C07D 495/06 (2013.01); C07D 498/04 (2013.01); C07C 2601/02 (2017.05); C07C 2601/08 (2017.05); C07C 2601/14 (2017.05); C07C 2601/16 (2017.05); C07C 2602/08 (2017.05); C07C 2602/10 (2017.05); C07C 2603/10 (2017.05);
Abstract
The present invention provides for certain sulfonyl ureas and related compounds which have advantageous properties and show useful activity in the inhibition of activation of the NLRP3 inflammasome. Such compounds are useful in the treatment of a wide range of disorders in which the inflammation process, or more specifically the NLRP3 inflammasome, have been implicated as being a key factor.