The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2020

Filed:

Dec. 30, 2014
Applicant:

Illumina, Inc., San Diego, CA (US);

Inventors:

Chenlu Hou, Belmont, CA (US);

Byoungsok Jung, Atherton, CA (US);

Yir-Shyuan Wu, Albany, CA (US);

Tarun Khurana, Fremont, CA (US);

Assignee:

ILLUMINA, INC., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); C40B 60/00 (2006.01); C12Q 1/6874 (2018.01); C12Q 1/68 (2018.01);
U.S. Cl.
CPC ...
B01L 3/502715 (2013.01); B01L 3/502761 (2013.01); C12Q 1/6874 (2013.01); B01L 2300/0636 (2013.01); B01L 2400/0415 (2013.01);
Abstract

Disclosed are methods and systems concerning flow cells for sequencing a nucleic acid sample that may be characterized by the following components: (a) a substrate having an inner surface facing a library sequencing region, and an outer surface; (b) a plurality of a plurality of forward and reverse amplification primers immobilized over the inner surface and providing a nucleic acid library capture surface of the library sequencing region; (c) a plurality of electrodes disposed along the inner surface directly under at least some of the forward and reverse amplification primers, and configured to provide, when charged, an electric field through the library capture surface and into the library sequencing region; (d) electrical leads connected to the plurality of electrodes to permit the electrodes to be independently addressable; and (e) fluidic couplings configured to deliver a plurality of nucleic acid libraries to the flow cell during different time periods.


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