The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2020

Filed:

Oct. 29, 2014
Applicant:

The University of Akron, Akron, OH (US);

Inventors:

Matthew Becker, Stow, OH (US);

Darrell Reneker, Akron, OH (US);

Yaohua Gao, Akron, OH (US);

Assignee:

THE UNIVERSITY OF AKRON, Akron, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/18 (2006.01); A61L 27/58 (2006.01); C08G 71/02 (2006.01); A61F 2/07 (2013.01); D01D 5/00 (2006.01); D01F 6/68 (2006.01); D01F 6/84 (2006.01); A61F 2/82 (2013.01);
U.S. Cl.
CPC ...
A61L 27/18 (2013.01); A61F 2/07 (2013.01); A61F 2/82 (2013.01); A61L 27/58 (2013.01); C08G 71/02 (2013.01); D01D 5/003 (2013.01); D01F 6/68 (2013.01); D01F 6/84 (2013.01); A61F 2230/0069 (2013.01); C08G 2230/00 (2013.01);
Abstract

Embodiments relate to amino acid-based poly(ester urea)s with amino acid residues selected L-leucine, L-isoleucine, L-valine or combinations thereof. The amino acid-based poly(ester urea)S may optionally include a second amino acid residue selected from proteinogenic amino acids and non-proteinogenic amino acids. The amino acid-based poly(ester urea)s are particular useful for the preparation of vascular grafts. Due to the biocompatibility of the amino acid-based poly(ester urea)s, vascular grafts prepared from amino acid-based poly(ester urea)s with small internal diameters (i.e. less than 5 mm) may be prepared and inserted into a patient or animal, and provide a substantial decrease in the risk of failure compared to conventional polymers used in vascular grafts.


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