The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2020
Filed:
Jan. 18, 2018
Applicant:
The Medical College of Wisconsin, Inc., Milwaukee, WI (US);
Inventors:
Brian Volkman, Muskego, WI (US);
Joshua Ziarek, Boston, MA (US);
Christopher Veldkamp, Milwaukee, WI (US);
Francis Peterson, Racine, WI (US);
Assignee:
The Medical College of Wisconsin, Inc., Milwaukee, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); A61K 38/19 (2006.01); C07K 14/52 (2006.01);
U.S. Cl.
CPC ...
A61K 38/195 (2013.01); C07K 14/521 (2013.01);
Abstract
The present invention provides a CXCL12peptide engineered to resist peptide-induced dimerization by maintaining steric repulsion of the chemokine helix, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of cancer, inflammatory disorders, autoimmune disease, and HIV/AIDS.