The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2020
Filed:
Jun. 08, 2018
Applicant:
Five Prime Therapeutics, Inc., South San Francisco, CA (US);
Inventors:
Thomas Harding, San Francisco, CA (US);
Servando Palencia, San Francisco, CA (US);
Li Long, Lafayette, CA (US);
Kevin Hestir, Kensington, CA (US);
Assignee:
Five Prime Therapeutics, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 45/06 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); C07K 14/71 (2006.01); C12Q 1/6813 (2018.01); C12Q 1/686 (2018.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 38/179 (2013.01); A61K 39/395 (2013.01); A61K 45/00 (2013.01); A61K 45/06 (2013.01); C07K 14/71 (2013.01); C12Q 1/686 (2013.01); C12Q 1/6813 (2013.01); G01N 33/5005 (2013.01); C07K 2319/30 (2013.01);
Abstract
Methods of treating cancers comprising FGFR1 gene amplification are provided. In some embodiments, the methods comprise administering a fibroblast growth factor receptor 1 (FGFR1) extracellular domain (ECD) and/or an FGFR1 ECD fusion molecule. In some embodiments, the methods comprise administering a fibroblast growth factor receptor 1 (FGFR1) extracellular domain (ECD) and/or an FGFR1 ECD fusion molecule in combination with at least one additional therapeutic agent.