The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2020
Filed:
May. 21, 2015
Korea Institute of Oriental Medicine, Daejeon, KR;
Jin Sook Kim, Seoul, KR;
Junghyun Kim, Daejeon, KR;
Chan-Sik Kim, Daejeon, KR;
Eunjin Shon, Daejeon, KR;
Yun Mi Lee, Daejeon, KR;
Young Sook Kim, Daejeon, KR;
Sojin Choi, Daejeon, KR;
Ik Soo Lee, Daejeon, KR;
Dong Ho Jung, Daejeon, KR;
Bo-Jeong Pyun, Daejeon, KR;
Seung-Hyun Jung, Daejeon, KR;
Korea Institute of Oriental Medicine, Daejeon, KR;
Abstract
The present invention relates to a pharmaceutical composition for preventing or treating angioedema, containing as an active ingredient a peony root extract or an extract of a mixture of peony root and licorice. In particular, the extract of a mixture of peony root and licorice according to the present invention inhibits the excessive generation of advanced glycation end products, which may cause macular degeneration, inhibits blood-retinal barrier breakdown causing retinal edema in various animal models, protects or treats a subretinal region causing dry macular degeneration, inhibits angiogenesis causing wet macular degeneration, and thus can be usefully used as an active ingredient for the composition for preventing and treating angioedema including macular degeneration, macular edema, retinal edema, or varicose veins.