The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2020

Filed:

Oct. 06, 2017
Applicant:

Jubilant Generics Limited, Noida, Uttar Pradesh, IN;

Inventors:

Kamal Surendrakumar Mehta, Noida, IN;

Saurabh Srivastava, Noida, IN;

Dinesh Kumar, Noida, IN;

Amit Kumar Jha, Noida, IN;

Subash Chandra Mohanta, Noida, IN;

Sunil Kumar Panda, Noida, IN;

Ganesh Vinayak Gat, Noida, IN;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); A61K 9/00 (2006.01); A61K 9/50 (2006.01); A61P 1/04 (2006.01); A61K 47/10 (2017.01); A61K 47/20 (2006.01); A61K 47/38 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4439 (2013.01); A61K 9/0095 (2013.01); A61K 9/5047 (2013.01); A61K 9/5073 (2013.01); A61K 9/5089 (2013.01); A61K 47/10 (2013.01); A61K 47/20 (2013.01); A61K 47/38 (2013.01); A61P 1/04 (2018.01); A61K 9/5026 (2013.01);
Abstract

The present invention discloses stable delayed release multiparticulate powder for oral suspension of proton pump inhibitor compounds comprising: a) a core with an effective amount of proton pump inhibitor and at least one or more pharmaceutical excipients, b) at least one water-soluble seal coating over core c) at least one enteric coating layer over the seal coat wherein the said core comprises disintegrant (0-10%) and/or surfactant (0-2%) w/w of core. The prior art discloses restrictive formulation technique and suggest high amount of various excipients to achieve desired technical attributes. The prepared test formulations exhibited desired pharmaceutical technical attributes like drug release, assay, stability, no polymorphic change, reduced sticking to nasogastric and gastronomy tubes, and packaging material.


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