The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2020
Filed:
Jun. 01, 2016
Bantam Pharmaceutical, Llc, New York, NY (US);
M. Arshad Siddiqui, Newton, MA (US);
Stephane Ciblat, Montreal, CA;
Martin Dery, Montreal, CA;
Lea Constantineau-Forget, Montreal, CA;
Chantal Grand-Maitre, Montreal, CA;
Xiangyu Guo, Montreal, CA;
Sanjay Srivastava, Pierrefonds, CA;
Gerald W. Shipps, Boston, MA (US);
Alan B. Cooper, Kenilworth, NJ (US);
Nicolas Bruneau-Latour, Montreal, CA;
Vu Linh Ly, Montreal, CA;
Bantam Pharmaceutical, LLC, New York, NY (US);
Abstract
Disclosed are pyrazole compounds, as well as pharmaceutical compositions and methods of use thereof. One embodiment is a compound having the structure (I) and pharmaceutically acceptable salts and/V-oxides thereof, wherein X, X, Z, Z, the ring system denoted by 'a', R, A, L, A, L, L, Q, L, R, A, L, A, L, R, L, and Rare as described herein. In certain embodiments, compounds disclosed herein disrupt the eIF4E/eiF4G interaction, and can be used to treat hyperproliferative disorder, a neurological disease or disorder, or autism.