The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2020

Filed:

Dec. 28, 2015
Applicant:

Biochemics, Inc., Danvers, MA (US);

Inventors:

Stephen G. Carter, Andover, MA (US);

Zhen Zhu, Andover, MA (US);

Kanu Patel, Londonderry, NH (US);

John J. Masiz, Topsfield, MA (US);

Assignee:

BioChemics, Inc., Danvers, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/26 (2006.01); A61K 31/192 (2006.01); A61K 47/22 (2006.01); A61K 31/05 (2006.01); A61K 9/00 (2006.01); A61K 31/427 (2006.01); A61K 31/415 (2006.01); A61K 9/06 (2006.01); A61K 31/19 (2006.01); A61K 31/426 (2006.01); A61K 45/06 (2006.01); A61K 47/02 (2006.01); A61K 31/455 (2006.01); A61F 13/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/192 (2013.01); A61K 9/0014 (2013.01); A61K 9/06 (2013.01); A61K 31/05 (2013.01); A61K 31/19 (2013.01); A61K 31/415 (2013.01); A61K 31/426 (2013.01); A61K 31/427 (2013.01); A61K 31/455 (2013.01); A61K 45/06 (2013.01); A61K 47/02 (2013.01); A61K 47/22 (2013.01); A61K 47/26 (2013.01); A61F 2013/00906 (2013.01);
Abstract

A formulation and method for delivery of bioactive substances when applied to, or within, the skin or other exterior region of a mammal. for example, a patient, includes a vasoactive agent; an osmolyte; and an active ingredient. The formulation is sufficiently hygroscopic so as to create a condition of hypertonicity when absorbed by the skin. When the formulation is applied to the skin, the vasoactive agent can be delivered to the dermis so as to contact the vasculature of a patient.


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