The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2020

Filed:

Jul. 07, 2016
Applicant:

Collagen Matrix, Inc., Oakland, NJ (US);

Inventors:

Shu-Tung Li, Oakland, NJ (US);

Natsuyo Shishido Lee, Oakland, NJ (US);

Debbie Yuen, Woodcliff Lake, NJ (US);

Assignee:

Collagen Matrix, Inc., Oakland, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61F 2/00 (2006.01); A61F 2/02 (2006.01); A61L 27/24 (2006.01); A61L 27/26 (2006.01); A61L 27/48 (2006.01);
U.S. Cl.
CPC ...
A61F 2/0077 (2013.01); A61F 2/02 (2013.01); A61L 27/24 (2013.01); A61L 27/26 (2013.01); A61L 27/48 (2013.01); A61F 2002/009 (2013.01); A61L 2430/34 (2013.01);
Abstract

A density gradient biopolymeric matrix implant is disclosed. The implant includes a first homogeneous matrix layer and a second homogeneous matrix layer having a density different from that of the first homogeneous matrix layer. Biopolymeric fibers at the surface of the first homogeneous matrix layer are physically in contact with and cross-linked to the biopolymeric fibers at the surface of the second homogeneous matrix layer. Also disclosed is a three-dimensional density gradient biopolymeric matrix implant that includes a first homogeneous matrix surrounding a second homogeneous matrix having a different density. Biopolymeric fibers at an inner surface of the first homogeneous matrix are physically in contact with and cross-linked to biopolymeric fibers at an outer surface of the second homogeneous matrix. Furthermore, methods for preparing the density gradient biopolymeric matrix implant and the three-dimensional density gradient biopolymeric matrix implant are provided.


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