The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 14, 2020

Filed:

Mar. 14, 2014
Applicant:

Georgetown University, Washington, DC (US);

Inventors:

Xiong Jiang, Falls Church, VA (US);

Maximilian Riesenhuber, Vienna, VA (US);

Assignee:

Georgetown University, Washington, DC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01R 33/48 (2006.01); A61B 5/055 (2006.01); A61B 5/00 (2006.01);
U.S. Cl.
CPC ...
G01R 33/4806 (2013.01); A61B 5/0042 (2013.01); A61B 5/055 (2013.01); A61B 5/4088 (2013.01); A61B 5/4839 (2013.01); A61B 2576/026 (2013.01);
Abstract

Provided herein are methods related to identifying an early, asymptomatic (prodromal) stage of a neurodegenerative disease or identifying a subject with a symptomatic neurodegenerative disease, including, for example, mild cognitive impairment (MCI), Alzheimer's Disease (AD), or HIV-associated neurocognitive disorder (HAND), using functional MRI data from the subject. Methods are also provided for treating a subject identified with the methods taught herein and for modifying or selecting treatment based on the results of fMRI. Methods are also available for staging neurodegenerative disease and for identifying agents useful in treating them.


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