The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 14, 2020

Filed:

Jun. 25, 2013
Applicant:

University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Inventors:

John A. Kellum, Pittsburgh, PA (US);

Christopher W. Seymour, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G01N 33/68 (2006.01); G01N 33/52 (2006.01); G01N 33/49 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5091 (2013.01); G01N 33/5023 (2013.01); G01N 33/521 (2013.01); G01N 33/6848 (2013.01); G01N 33/6893 (2013.01); C12Q 2600/118 (2013.01); G01N 2570/00 (2013.01); G01N 2800/12 (2013.01); G01N 2800/26 (2013.01); G01N 2800/56 (2013.01); G01N 2800/60 (2013.01); G01N 2800/7066 (2013.01);
Abstract

The present invention describes a global metabolomic profile of patients with community acquired pneumonia (CAP) and sepsis. The metabolomic profile of endogenous small molecules blood was determined using mass-spectrometry. The global metabolomic profile in plasma demonstrated broad differences between CAP and sepsis patients when comparing those who do and do not survive at 90 days. Increases in specific metabolite biomarkers displayed on a heat map provide early diagnosis of these medical conditions to allow for early intervention and aggressive treatment.


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