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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10533207 B1

PDFFull Text
Date of Patent:
Jan. 14, 2020

Filed:

Oct. 16, 2014

Bioactivity testing structure for single cell tracking using gelling agents

Applicant:

Quantamatrix Inc., Seoul, KR;

Inventors:

Yong-Gyun Jung, Seoul, KR;

Eun Guen Kim, Gunpo-si, KR;

Jung Heon Yoo, Yongin-si, KR;

Kyung-Ock Park, Ansan-si, KR;

Sunghoon Kwon, Seoul, KR;

Jungil Choi, Seoul, KR;

Hee jin Kim, Seoul, KR;

Sung Weon Ryoo, Yongin-si, KR;

Haeun Kim, Iksan-si, KR;

Hyeon Ju Jeoung, Chuncheon-si, KR;

Eun Hee Lee, Cheongju-si, KR;

Hyejin Kim, Cheongju-si, KR;

Assignee:

QUANTAMATRIX INC., Seoul, KR;

Attorney:

STIP Law Group, LLC

Primary Examiner:

Nathan A Bowers

Int. Cl.
CPC ...
C12M 1/00 (2006.01); C12M 3/00 (2006.01); C12Q 1/18 (2006.01); C12Q 1/02 (2006.01); C12M 1/18 (2006.01); C12M 1/12 (2006.01); C12M 1/32 (2006.01); C12M 1/16 (2006.01); C12M 1/14 (2006.01); C12M 1/34 (2006.01); C12M 1/22 (2006.01); C12Q 1/04 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/18 (2013.01); C12M 1/14 (2013.01); C12M 1/16 (2013.01); C12M 1/18 (2013.01); C12M 23/10 (2013.01); C12M 23/12 (2013.01); C12M 23/20 (2013.01); C12M 23/22 (2013.01); C12M 25/14 (2013.01); C12M 29/04 (2013.01); C12M 29/26 (2013.01); C12M 41/46 (2013.01); C12Q 1/02 (2013.01); C12Q 1/04 (2013.01); G01N 2800/26 (2013.01);
Abstract

The present invention relates to a novel bioactivity testing structure for single cell tracking using a gelling agent and a bioactivity testing system including the testing structure. The present invention also relates to bioactivity testing, drug susceptibility testing, antibiotic screening, and diagnostic methods using the testing structure. The bioactivity testing structure of the present invention enables very rapid and simple drug susceptibility testing of bacteria, particularly, drug screening, and bacterial diagnosis. Particularly, the use of the testing structure enables DST and diagnosis of bacteria only by pretreatment without the need to concentrate human sputum samples irrespective of inoculum effect, ensuring rapid, accurate, and simple testing compared to conventional tuberculosis diagnosis or DST systems. In addition, the testing structure of the present invention simultaneously enables the diagnosis and drug susceptibility testing of tuberculosis. Therefore, the present invention provides an effective alternative to the prior art.

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