The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2020
Filed:
Mar. 18, 2016
Applicant:
University of Florida Research Foundation, Incorporated, Gainesville, FL (US);
Inventors:
William W. Hauswirth, Gainesville, FL (US);
Ji-Jing Pang, Gainesville, FL (US);
Assignee:
University of Florida Research Foundation, Incorporated, Gainesville, FL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61P 27/02 (2006.01); C12N 15/00 (2006.01); C12N 15/63 (2006.01); C12N 15/79 (2006.01); C12N 15/85 (2006.01); C12N 15/86 (2006.01); A61K 9/00 (2006.01); A61K 38/17 (2006.01); C07K 14/72 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61K 9/0048 (2013.01); A61K 38/177 (2013.01); A61K 48/0058 (2013.01); A61K 48/0075 (2013.01); A61P 27/02 (2018.01); C07K 14/723 (2013.01); C12N 15/85 (2013.01); C12N 2750/14143 (2013.01); C12N 2750/14171 (2013.01); C12N 2830/008 (2013.01); C12N 2830/50 (2013.01);
Abstract
Provided are nucleic acid sequences, recombinant adeno-associated viral particles, compositions, and methods related to treating cone monochromacies, such as blue cone monochromacy (BCM). Specifically, the nucleic acid sequences, recombinant adeno-associated viral particles, compositions, and methods involve use of an M-opsin gene operably linked to a cone-specific promoter. Further disclosed is the sequence of a cone-specific PR2.1 promoter.