The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2020
Filed:
Nov. 26, 2018
Applicant:
Invista North America S.á.r.l., Wilmington, DE (US);
Inventors:
Alex Van Eck Conradie, Eaglescliffe, GB;
Adriana Leonora Botes, Rosedale East, GB;
Assignee:
INVISTA North America S.á.r.l., Wilmington, DE (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/81 (2006.01); C12P 13/00 (2006.01); C12P 7/18 (2006.01); C12P 7/44 (2006.01); C12P 7/42 (2006.01); C12N 15/52 (2006.01); C12N 9/00 (2006.01); C12N 9/10 (2006.01); C12N 9/16 (2006.01); C12N 9/80 (2006.01); C12N 9/86 (2006.01); C12P 17/10 (2006.01); C12N 9/02 (2006.01);
U.S. Cl.
CPC ...
C12N 15/81 (2013.01); C12N 9/0008 (2013.01); C12N 9/0077 (2013.01); C12N 9/1029 (2013.01); C12N 9/1096 (2013.01); C12N 9/16 (2013.01); C12N 9/80 (2013.01); C12N 9/86 (2013.01); C12N 15/52 (2013.01); C12P 7/18 (2013.01); C12P 7/42 (2013.01); C12P 7/44 (2013.01); C12P 13/001 (2013.01); C12P 13/005 (2013.01); C12P 17/10 (2013.01); C12Y 102/01002 (2013.01); C12Y 102/99006 (2013.01); C12Y 114/15001 (2013.01); C12Y 203/01032 (2013.01); C12Y 206/01018 (2013.01); C12Y 206/01019 (2013.01); C12Y 206/01029 (2013.01); C12Y 206/01048 (2013.01); C12Y 206/01082 (2013.01); C12Y 301/02 (2013.01); C12Y 305/01062 (2013.01);
Abstract
This document describes biochemical pathways for producing adipic acid, caprolactam, 6-aminohexanoic acid, 6-hydroxyhexanoic acid, hexamethylenediamine or 1,6-hexanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl groups, in a C6 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on CoA-dependent elongation enzymes or analogues enzymes associated with the carbon storage pathways from polyhydroxyalkanoate accumulating bacteria.