The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2020
Filed:
May. 05, 2016
Jiangsu Micromedmark Biotech Co., Ltd., Jiangsu, CN;
Chenyu Zhang, Jiangsu, CN;
Ke Zeng, Jiangsu, CN;
Xi Chen, Jiangsu, CN;
Junfeng Zhang, Jiangsu, CN;
Hongwei Liang, Jiangsu, CN;
JIANGSU MICROMEDMARK BIOTECH CO., LTD., Jiangsu, CN;
Abstract
Provided are a new precursor miRNA and the applications in tumor therapy thereof. The precursor miRNA, from 5'- to 3′-end thereof, has the structure represented by formula (I). B1 is an anti-miRNA and/or siRNA to be expressed; B2 is a sequence substantially or completely complementary to B1, and B2 is not complementary to C; C is a sequence with stem-loop structure; A1 and A2 are independently hydrogen or optionally a RNA sequence consisting of 4 to 5 bases. The precursor miRNA can be processed to form an anti-miRNA and/or siRNA in hosts.