The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 14, 2020

Filed:

Apr. 22, 2015
Applicants:

Universite Grenoble Alpes, Saint Martin D'Heres, FR;

Centre National DE LA Recherche Scientifique, Paris, FR;

Inventors:

Jérôme Dupuy, Saint Quentin Sur Isère, FR;

Christine Hajjar, Bekaa, LB;

Mickaël Cherrier, Tullins, FR;

Franck Fieschi, Vif, FR;

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/00 (2006.01); C12Q 1/26 (2006.01); C12Q 1/28 (2006.01); G01N 33/52 (2006.01); C12N 9/02 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0036 (2013.01); C12Q 1/28 (2013.01); C12Y 106/03001 (2013.01); G01N 33/52 (2013.01); G01N 2333/90209 (2013.01);
Abstract

A NADPH oxidase (Nox) protein includes a domain including 3 to 7 transmembrane helices, and an amino acid sequence including at least 2 bis-histidyl motifs, wherein each of the bis-histidyl motifs consists of 2 histidine residues separated by 12, 13 or 14 amino acid residues. The Nox protein may be produced by a method that includes solubilizing a solution of cells expressing the Nox protein using a detergent from the maltoside family to suspend the Nox protein in the solution.


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