The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2020
Filed:
Apr. 19, 2018
Applicant:
Apogenix Ag, Heidelberg, DE;
Inventors:
Christian Gieffers, Dossenheim, DE;
Oliver Hill, Neckarsteinach, DE;
Meinolf Thiemann, Schriesheim, DE;
Tim Schnyder, Igersheim, DE;
Assignee:
Apogenix AG, Heidelberg, DE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); A61K 38/00 (2006.01); C12N 15/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70575 (2013.01); C12N 15/00 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01); C07K 2319/22 (2013.01); C07K 2319/30 (2013.01); C07K 2319/32 (2013.01); C07K 2319/35 (2013.01); C07K 2319/74 (2013.01);
Abstract
Provided herein are specific GITR receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a GITRL-associated disease or disorder. The GITR receptor agonist proteins provided herein comprise three soluble GITRL domains and an Fc fragment. The GITR receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.