The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 14, 2020

Filed:

Nov. 30, 2017
Applicant:

Portola Pharmaceuticals, Inc., South San Francisco, CA (US);

Inventors:

Shawn M. Bauer, Pacifica, CA (US);

Zhaozhong J. Jia, San Mateo, CA (US);

Mukund Mehrotra, South San Francisco, CA (US);

Yonghong Song, Foster City, CA (US);

Qing Xu, Foster City, CA (US);

Wolin Huang, Foster City, CA (US);

Chandrasekar Venkataramani, Redwood City, CA (US);

Jack W. Rose, San Mateo, CA (US);

Anjali Pandey, Fremont, CA (US);

Assignee:

PORTOLA PHARMACEUTICALS, INC., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 239/28 (2006.01); C07D 403/02 (2006.01); C07D 413/02 (2006.01); C07D 279/12 (2006.01); A61K 31/506 (2006.01); A61K 31/501 (2006.01); A61K 31/5377 (2006.01); A61K 31/551 (2006.01); A61K 31/541 (2006.01); C07D 417/12 (2006.01); A61K 31/4985 (2006.01); A61K 31/505 (2006.01); A61K 31/5355 (2006.01); C07D 239/48 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07D 417/12 (2013.01); A61K 31/4985 (2013.01); A61K 31/505 (2013.01); A61K 31/506 (2013.01); A61K 31/5355 (2013.01); A61K 31/5377 (2013.01); A61K 31/551 (2013.01); C07D 239/48 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/12 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01);
Abstract

The present invention is directed to topical pharmaceutical compositions of Formula (If) or pharmaceutically acceptable salt thereof, which act as inhibitors of syk and/or JAK kinase activity. The described topical pharmaceutical compositions are useful in preventing or treating a number of conditions mediated at least in part by syk and/or JAK kinase activity.


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