The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 14, 2020

Filed:

Jan. 10, 2017
Applicant:

Proteostasis Therapeutics, Inc., Boston, MA (US);

Inventors:

Megan Foley, Cambridge, MA (US);

Bradley Tait, Malden, MA (US);

Matthew Cullen, Braintree, MA (US);

Assignee:

Proteostasis Therapeutics, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/06 (2006.01); C07D 405/06 (2006.01); C07D 401/06 (2006.01); C07D 249/06 (2006.01); C07D 207/333 (2006.01); C07D 207/337 (2006.01); C07D 231/12 (2006.01); C07D 263/32 (2006.01); C07D 275/02 (2006.01); C07D 295/185 (2006.01); C07D 333/20 (2006.01); C07D 471/04 (2006.01); C07D 333/22 (2006.01);
U.S. Cl.
CPC ...
C07D 403/06 (2013.01); C07D 207/333 (2013.01); C07D 207/337 (2013.01); C07D 231/12 (2013.01); C07D 249/06 (2013.01); C07D 263/32 (2013.01); C07D 275/02 (2013.01); C07D 295/185 (2013.01); C07D 333/20 (2013.01); C07D 333/22 (2013.01); C07D 401/06 (2013.01); C07D 405/06 (2013.01); C07D 471/04 (2013.01);
Abstract

The present invention is directed to compounds having the Formulae (Ia-Ie), (II), (IIIa-IIId), (IVa-IVc), (Va-Vb), (VIa-VIe), (VII), (VIIIa-VIIIc), and (IX), pharmaceutically acceptable salts, prodrugs and solvates thereof, compositions of any of thereof and methods for the treatment of a condition associated with a dysfunction in proteostasis comprising an effective amount of these compounds.


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