The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2020
Filed:
Jun. 11, 2018
Amazentis SA, Ecublens, CH;
Christopher Rinsch, Morges, CH;
Rune A. Ringom, Uppsala, CH;
Amazentis SA, , CH;
Abstract
The invention provides compounds of formula (I) or salts thereof: wherein:A, B, C, D, W, X, Y and Z are as defined in the specification, and at least one of A, B, C, D, W, X, Y and Z is OR; each Rbeing independently H or C(═O)R, and at least one Rgroup being C(═O)R; where each Ris selected from:CHRNHR, where Ris H and Ris a group selected from CH, CHCH(CH), CH(CH)CHCH, CHPh, CH-3-(1H-indole), CHCHSCH, CHOH, CHOHCH, CHSH, CHSeH and CHPhpOH,wherein said Rgroup can optionally be substituted by one or more groups selected from halogen, cyano, nitro, ORor C-Calkyl;or Rand Rtogether with the C and N atoms to which they are attached form a 5-membered heteroalkyl ring, wherein said heteroalkyl ring can optionally be substituted by one or more groups selected from halogen, cyano, nitro, ORor C-Calkyl,wherein Ris C-Calkyl optionally substituted with one or more halogen, cyano or nitro groups. The compounds are effective pro-drugs for urolithins and they enable the ready delivery of urolithins to the site in the digestive tract where they can be absorbed into the body.