The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 14, 2020

Filed:

Jul. 20, 2016
Applicants:

Oregon Health & Science University, Portland, OR (US);

The United States Government As Represented BY the Department of Veterans, Washington, DC (US);

Inventors:

Michael Riscoe, Tualatin, OR (US);

Aaron Nilsen, Portland, OR (US);

Galen Miley, Portland, OR (US);

Rolf Winter, Portland, OR (US);

Sovitj Pou, Portland, OR (US);

Jane Xu Kelly, Portland, OR (US);

Rozalia Dodean, Portland, OR (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/22 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); A61P 33/00 (2006.01);
U.S. Cl.
CPC ...
C07D 215/22 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01);
Abstract

Disclosed are derivative compounds of ELQ-300 that include an ester at position 4. These compounds have enhanced properties relative to ELQ-300. Also disclosed are pharmaceutical compositions comprising the compounds and methods of treating and preventing malaria infections involving administering the pharmaceutical compositions to the subject.


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