The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2020
Filed:
Mar. 12, 2018
Nitto Denko Corporation, Osaka, JP;
Yoshiro Niitsu, Hokkaido, JP;
Victor Knopov, Oceanside, CA (US);
Joseph E. Payne, Oceanside, CA (US);
Zheng Hou, San Diego, CA (US);
John A. Gaudette, Poway, CA (US);
Violetta Akopian, Oceanside, CA (US);
Richard P. Witte, San Diego, CA (US);
Mohammad Ahmadian, Carlsbad, CA (US);
Loren A. Perelman, San Diego, CA (US);
Yasunobu Tanaka, Osaka, JP;
Priya Karmali, San Diego, CA (US);
Sridhar C. Nagarajan, San Diego, CA (US);
Nitto Denko Corporation, Osaka, JP;
Abstract
Here described is a method of delivery of a drug to a stellate cell using a composition comprising a compound of formula I: wherein Rand Rare independently selected from Cto Calkyl, Cto Calkenyl, and oleoyl; Rand Rare independently selected from Cto Calkyl and Cto Calkanol; X is selected from —CH—, —S—, and —O—, or X is absent; Y is selected from —(CH), —S(CH)—, —O(CH)—, -thiophene-, —SO(CH)—, and ester; n═1-4; a═1-4; b═1-4; c═1-4; and Zis a counterion.