The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2020
Filed:
Mar. 13, 2015
Ramot AT Tel-aviv University Ltd., Tel-Aviv, IL;
Ronit Satchi-Fainaro, Tel-Aviv, IL;
Doron Shabat, Tel-Aviv, IL;
Rachel Blau, Tel-Aviv, IL;
Yana Epshtein, Tel-Aviv, IL;
Hemda Baabur-Cohen, Tel-Aviv, IL;
Shiran Ferber, Tel-Aviv, IL;
Orit Redy-Keisar, Tel-Aviv, IL;
Einat Kisin-Finfer, Tel-Aviv, IL;
Ramot at Tel-Aviv University Ltd., Tel-Aviv, IL;
Abstract
Polymeric systems useful for theranostic applications are disclosed. The polymeric systems comprise a fluorescent or fluorogenic moiety and a therapeutically active agent, each attached to the same or different polymeric moiety. The polymeric systems are designed such that a fluorescent signal is generated in response to a chemical event, preferably upon contacting an analyte (e.g., an enzyme) that is over-expressed in a diseased tissue or organ. Probes useful for inclusion in such polymeric systems, processes of preparing such probes and the polymeric systems, and uses thereof in diagnostic and/or theranostic applications are also disclosed.