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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10532057 B1

PDFFull Text
Expired
Date of Patent:
Jan. 14, 2020

Filed:

Aug. 26, 2016

Brain-penetrant chromone oxime derivative for the therapy of levodopa-induced dyskinesia

Applicant:

Prexton Therapeutics SA, Geneva, CH;

Inventors:

Delphine Charvin, Gex, FR;

François Conquet, Beaumont, FR;

Assignee:

Prexton Therapeutics SA, Plan les Ouates, CH;

Attorney:

Wolf, Greenfield & Sacks, P.C.

Primary Examiner:

Savitha M Rao

Int. Cl.
CPC ...
A61K 31/5377 (2006.01); C07D 495/04 (2006.01); A61P 25/14 (2006.01); A61P 25/16 (2006.01); A61K 9/00 (2006.01); A61K 31/198 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 9/0053 (2013.01); A61K 31/198 (2013.01); A61K 45/06 (2013.01); A61P 25/14 (2018.01); A61P 25/16 (2018.01); C07D 495/04 (2013.01);
Abstract

The present invention provides a chromone oxime derivative of formula (I), which is a modulator of nervous system receptors sensitive to the neuroexcitatory amino acid glutamate and presents an advantageously high brain exposure upon oral administration, for the treatment or prevention of levodopa-induced dyskinesia. The present invention also provides an improved therapy of Parkinson's disease, using the chromone oxime derivative of formula (I) in combination with ievodopa.

Find Patent Forward Citations

Charvin, Delphine. (2020). Brain-penetrant chromone oxime derivative for the therapy of levodopa-induced dyskinesia (U.S. Patent No. 10532057). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10532057

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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