The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 14, 2020

Filed:

Nov. 07, 2016
Applicants:

Catherine M. Shachaf, Los Gatos, CA (US);

Amit Shachaf, Palo Alto, CA (US);

Inventors:

Catherine M. Shachaf, Los Gatos, CA (US);

Amit Shachaf, Palo Alto, CA (US);

Assignee:

ORLUCENT, INC., Los Gatos, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61K 49/00 (2006.01); A61K 51/00 (2006.01); A61B 90/30 (2016.01);
U.S. Cl.
CPC ...
A61B 5/444 (2013.01); A61B 5/0071 (2013.01); A61B 5/0077 (2013.01); A61K 49/0004 (2013.01); A61K 49/0006 (2013.01); A61K 49/0017 (2013.01); A61K 51/00 (2013.01); A61B 2090/306 (2016.02); A61B 2560/0431 (2013.01); A61B 2562/0233 (2013.01); A61B 2562/046 (2013.01); A61B 2562/164 (2013.01); A61B 2562/166 (2013.01); A61B 2576/02 (2013.01);
Abstract

Methods and compositions are provided for the analysis of skin surfaces to determine the presence of neoplastic tissue. In the methods of the invention, a composition comprising a florescent probe that binds to a specific neoplasia associated marker is applied topically to the area of interest. After topical administration, the probe preferentially binds to markers associated in neoplastic lesions in situ, which binding is detected with a compact illumination unit that provides illumination at a wavelength appropriate for image acquisition. The illumination unit comprises a light source and fiber optic bundle to direct the light towards the area of examination. A detection unit is used to capture and record an image of the area of investigation. The detection unit may be a digital camera, film camera, etc. A mapping module may also be provided to catalogue the site of examination.


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