The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2020
Filed:
Jan. 18, 2016
Erasmus University Medical Center Rotterdam, Rotterdam, NL;
Gerwin Jan Puppels, Schiedam, NL;
Elisa Maria Barroso, Rotterdam, NL;
Tom Christian Bakker Schut, Zoetermeer, NL;
Roeland W. H. Smits, Rhoon, NL;
Peter Jacobus Caspers, Capelle aan den IJssel, NL;
Senada Koljenovic, Rotterdam, NL;
ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM, Rotterdam, NL;
Abstract
Method and instrument for analysing a tissue sample. Localized concentrations of an analyte are measured at a plurality of spaced apart locations around a controlled depth. Spatial variance of the analyte is calculated based on the measured analyte concentrations. The procedure is repeated while varying the controlled depth to obtain the spatial variance as a function of depth. Tissue at a particular depth may be evaluated as tumour tissue when the spatial variance is below the threshold. For example, a section distance is calculated between the tissue surface and a depth where the measured spatial variance crosses a predetermined threshold variance. Feedback can be provided based on a comparison between a calculated section distance and a pre-set minimum section margin.