The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2020
Filed:
Mar. 11, 2016
Wayne State University, Detroit, MI (US);
Sorin Draghici, Detroit, MI (US);
Tin Chi Nguyen, Detroit, MI (US);
WAYNE STATE UNIVERSITY, Detroit, MI (US);
Abstract
Disease subtyping is accomplished by a computer-implemented algorithm that manipulates a first genetic dataset to construct a set of first connectivity matrices. To this set of matrices Gaussian noise is introduced to generate a perturbed dataset. The computer-implemented algorithm assesses which of the set of first connectivity matrices was least affected by introduction of noise and that matric is used to define the optimal clustering. Once the optimal clustering is determined, computer-implemented supervised classification is performed to determine, for a particular patient, with which disease subtype cluster that person's genetic data most closely aligns. Armed with this knowledge, the treatment regimen is specified with much higher likelihood of success.