The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2020

Filed:

Jun. 04, 2015
Applicant:

Institut D'investigació Biomèdica DE Bellvitge (Idibell), Hospitalet de Llobregat, ES;

Inventors:

Oriol Bestard Matamoros, Barcelona, ES;

Marc Lúcia Perrez, Barcelona, ES;

Josep Maria Grinyó Boira, Castelldefels, ES;

Josep Maria Cruzado Garrit, Barcelona, ES;

Joan Torras Ambros, Barcelona, ES;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 33/50 (2006.01); G01N 33/564 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6854 (2013.01); G01N 33/5052 (2013.01); G01N 33/564 (2013.01); G01N 33/56977 (2013.01); G01N 2800/24 (2013.01); G01N 2800/245 (2013.01); G01N 2800/50 (2013.01);
Abstract

The invention relates methods for detecting antibody-secreting B-cells specific for at least an HLA in a subject. The invention also relates to kits for developing said methods and to the use of said methods for determining the risk of a subject having humoral rejection against an allogeneic transplant, for determining the risk of a subject of suffering endarteritis associated with post-transplant humoral rejection after allogeneic organ or tissue transplant, for selecting a subject to receive a transplant, and for determining the presence of humoral sensitization against HLA.


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