The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2020
Filed:
Jul. 07, 2015
Applicant:
Allergan, Inc., Irvine, CA (US);
Inventors:
Ron S. Broide, San Marcos, CA (US);
Brian Cai, Irvine, CA (US);
Ester Fernandez-Salas, Ann Arbor, MI (US);
Joseph Francis, Laguna Niguel, CA (US);
Catherine Rheaume, Irvine, CA (US);
Assignee:
Allergan, Inc., Irvine, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/573 (2006.01); C07K 16/18 (2006.01);
U.S. Cl.
CPC ...
G01N 33/573 (2013.01); C07K 16/18 (2013.01); C07K 2317/24 (2013.01); C07K 2317/34 (2013.01); C07K 2317/567 (2013.01); C07K 2317/72 (2013.01); G01N 2333/952 (2013.01);
Abstract
Methods and compositions for detecting BoNT/A enzymatic activity in tissues or a tissue sample are described herein. The invention encompasses antibodies that bind preferentially to BoNT/A cleaved SNAP25 and is able to preferentially detect BoNT/A cleaved SNAP25, as compared to intact (non-cleaved) SNAP25, in a tissue sample.