The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2020

Filed:

Jul. 02, 2014
Applicant:

Technische Universitaet Dresden, Dresden, DE;

Inventors:

Weilin Lin, Dresden, DE;

Robert Wieduwild, Dresden, DE;

Luca Mannocci, Eiken, CH;

Jana Herrmann, Dresden, DE;

Yixin Zhang, Dresden, DE;

Francesco Reddavide, Dresden, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); G01N 33/543 (2006.01); C12Q 1/6837 (2018.01);
U.S. Cl.
CPC ...
G01N 33/54306 (2013.01); C12Q 1/6837 (2013.01); G01N 33/54353 (2013.01); G01N 33/54393 (2013.01);
Abstract

In a method and arrangement for detecting binding events of molecules, at least one second molecule covalently bound to a ligand, and optionally bonded to a third molecule bound to a ligand, forms a specific non-covalent fond with a first molecule immobilised on a bioactive surface by a covalent bond, and binding events between an analyte molecule and the second-molecule bound ligand are detected by an analytical measuring method, wherein the specific non-covalent bond between the first and second molecules is breakable by supplying a buffer solution, and, hence, a specific ligand, or two, different specific ligands are made available on the bioactive surface in an easily reversible manner.


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