The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2020

Filed:

Feb. 20, 2015
Applicants:

Merck Patent Gmbh, Darmstadt, DE;

Somalogic, Inc., Boulder, CO (US);

Inventors:

Anne Baumstummler, Gertwiller, FR;

Frederic Marc-Kreucher, Itterswiller, FR;

David Lehmann, Andolsheim, FR;

Urs Ochsner, Denver, CO (US);

Nebojsa Janjic, Boulder, CO (US);

Assignees:

Merck Patent GmbH, Darmstadt, DE;

SOMALOGIC, Inc., Boulder, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); G01N 15/14 (2006.01); G01N 21/64 (2006.01); C12Q 1/689 (2018.01); G01N 15/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/689 (2013.01); G01N 15/1436 (2013.01); G01N 21/6428 (2013.01); G01N 2015/0065 (2013.01); G01N 2021/6439 (2013.01); G01N 2201/06113 (2013.01);
Abstract

The present invention relates to a method of detecting a microorganism, in particular, in a sample, comprising the steps of a) incubating the sample with a slow off-rate modified aptamer (SOMAmer) comprising a fluorescent label, b) optionally washing the sample, c) analyzing the sample by a fluorescence-based detection method. The invention further relates to a slow off-rate modified aptamer comprising a fluorescent label, wherein the SOMAmer comprises a nucleotide sequence specific for, its use for detectingcells in a sample, and to a microarray or biosensor and a kit comprising at least one of such SOMAmers comprising a fluorescent label.


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