The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2020
Filed:
Aug. 29, 2016
Applicant:
Research Development Foundation, Carson City, NV (US);
Inventors:
George Georgiou, Austin, TX (US);
Chang-Han Lee, Austin, TX (US);
Assignee:
Research Development Foundation, Carson City, NV (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/00 (2006.01); C07K 16/00 (2006.01); C12P 21/08 (2006.01); A61K 39/395 (2006.01); A61K 39/40 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/283 (2013.01); C07K 16/00 (2013.01); C07K 16/2887 (2013.01); C07K 2317/14 (2013.01); C07K 2317/41 (2013.01); C07K 2317/524 (2013.01); C07K 2317/70 (2013.01); C07K 2317/75 (2013.01); C07K 2317/92 (2013.01); C07K 2319/30 (2013.01);
Abstract
In some aspects, mutant or variant Fc domains are provided that can exhibit increased affinity or selectivity for FcγRIIB. The variant Fc domain may be a mutant IgG1 Fc domain. In some embodiments, a mutant or variant Fc domain may be present in a therapeutic antibody such as, e.g., an agonistic antibody. Additional methods for using and identifying mutant Fc domains are also provided.
Quick Actions:
Georgiou, George. (2020). Engineered antibody fc variants (U.S. Patent No. 10526408). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10526408
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile