The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2020

Filed:

Jun. 02, 2015
Applicant:

Immunomax Co., Ltd., Seoul, KR;

Inventors:

Se-Ho Park, Seoul, KR;

Eunbi Yi, Seoul, KR;

Assignee:

IMMUNOMAX CO., LTD., Seoul, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C12N 7/00 (2006.01); C07K 14/705 (2006.01); A61K 39/12 (2006.01); C07K 14/005 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70596 (2013.01); A61K 39/12 (2013.01); C07K 14/005 (2013.01);
Abstract

The present invention relates to a method for promoting virus infection and increasing virus production, by using a cell line having lost Bst2 gene functions and, more specifically, to a method for promoting target virus infection and increasing target virus production, in addition to promoting virus budding and inhibiting host cell apoptosis by removing the Bst2 gene from a cell line having the ability to produce a virus. According to the present invention, the method for promoting target virus infection and increasing target virus production, by using an animal cell line having lost Bst2 gene functions, can improve production yields of a target virus and an antigen protein, and thus can be useful for the preparation of vaccines for treating and preventing viral diseases.


Find Patent Forward Citations

Loading…