IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10526316 B1

PDFFull Text
Date of Patent:
Jan. 07, 2020

Filed:

Oct. 07, 2016

Quinoxaline and pyridopyrazine derivatives as pi3kβ inhibitors

Applicant:

Janssen Pharmaceutica NV, Beerse, BE;

Inventors:

Patrick Rene Angibaud, Saint Pierre d'Autils, FR;

Olivier Alexis Georges Querolle, Saint Vigor, FR;

Didier Jean-Claude Berthelot, La Neuville Chant d'Oisel, FR;

Christophe Meyer, Les Authieux sur le Port St Ouen, FR;

Matthieu Philippe Victor Willot, Dusseldorf, DE;

Lieven Meerpoel, Beerse, BE;

Thierry Francois Alain Jean Jousseaume, Schaffhausen, CH;

Assignee:

Janssen Pharmaceutica NV, Beerse, BE;

Attorney:
Primary Examiner:

Jeffrey S Lundgren

Assistant Examiner:

Michael J Schmitt

Int. Cl.
CPC ...
C07D 403/10 (2006.01); C07D 487/04 (2006.01); C07D 495/10 (2006.01); C07D 498/10 (2006.01); C07D 471/04 (2006.01); C07D 241/42 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 413/10 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 403/04 (2006.01); C07D 403/06 (2006.01); C07D 413/04 (2006.01); C07D 413/06 (2006.01); C07D 241/14 (2006.01); C07D 417/04 (2006.01); C07D 487/02 (2006.01); C07D 491/10 (2006.01); C07D 513/10 (2006.01);
U.S. Cl.
CPC ...
C07D 403/10 (2013.01); C07D 241/14 (2013.01); C07D 241/42 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 403/04 (2013.01); C07D 403/06 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 413/04 (2013.01); C07D 413/06 (2013.01); C07D 413/10 (2013.01); C07D 417/04 (2013.01); C07D 471/04 (2013.01); C07D 487/02 (2013.01); C07D 487/04 (2013.01); C07D 491/10 (2013.01); C07D 495/10 (2013.01); C07D 498/10 (2013.01); C07D 513/10 (2013.01);
Abstract

The present invention relates to substituted quinoxaline and pyridopyrazine derivatives of Formula (I) wherein the variables have the meaning defined in the claims. The compounds according to the present invention are useful as pI3Kβ inhibitors. The invention further relates to pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.

Find Patent Forward Citations

Loading…