The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2020

Filed:

Apr. 22, 2016
Applicant:

Constellation Pharmaceuticals, Inc., Cambridge, MA (US);

Inventors:

Brian K. Albrecht, Cambridge, MA (US);

James Edmund Audia, Cambridge, MA (US);

Alexandre Côté, Cambridge, MA (US);

Martin Duplessis, Somerville, MA (US);

Victor S. Gehling, Somerville, MA (US);

Jean-Christophe Harmange, Andover, MA (US);

Rishi G. Vaswani, Lexington, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/22 (2006.01); C07D 211/26 (2006.01); C07D 309/20 (2006.01); C07D 215/44 (2006.01); C07D 317/28 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 403/04 (2006.01); C07D 403/06 (2006.01); C07D 403/10 (2006.01); C07D 405/04 (2006.01); C07D 239/30 (2006.01); C07C 215/44 (2006.01); C07D 417/06 (2006.01); C07D 263/32 (2006.01); C07D 205/12 (2006.01); C07D 207/32 (2006.01); C07D 211/36 (2006.01); C07D 213/64 (2006.01); C07D 305/06 (2006.01); C07C 255/58 (2006.01); C07C 211/09 (2006.01); C07C 211/36 (2006.01); C07C 211/40 (2006.01); C07C 215/14 (2006.01); C07C 217/08 (2006.01); C07C 229/10 (2006.01); C07C 229/38 (2006.01); C07C 229/46 (2006.01); C07C 233/41 (2006.01); C07C 237/06 (2006.01); C07C 255/24 (2006.01); C07C 215/42 (2006.01); C07C 255/30 (2006.01); C07D 211/58 (2006.01); C07D 211/76 (2006.01); C07D 213/38 (2006.01); C07D 213/69 (2006.01); C07D 213/73 (2006.01); C07D 295/195 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 211/26 (2013.01); A61P 35/00 (2018.01); C07C 211/09 (2013.01); C07C 211/36 (2013.01); C07C 211/40 (2013.01); C07C 215/14 (2013.01); C07C 215/42 (2013.01); C07C 215/44 (2013.01); C07C 217/08 (2013.01); C07C 229/10 (2013.01); C07C 229/38 (2013.01); C07C 229/46 (2013.01); C07C 233/41 (2013.01); C07C 237/06 (2013.01); C07C 255/24 (2013.01); C07C 255/30 (2013.01); C07C 255/58 (2013.01); C07D 205/12 (2013.01); C07D 207/32 (2013.01); C07D 211/22 (2013.01); C07D 211/36 (2013.01); C07D 211/58 (2013.01); C07D 211/76 (2013.01); C07D 213/38 (2013.01); C07D 213/64 (2013.01); C07D 213/69 (2013.01); C07D 213/73 (2013.01); C07D 215/44 (2013.01); C07D 239/30 (2013.01); C07D 263/32 (2013.01); C07D 295/195 (2013.01); C07D 305/06 (2013.01); C07D 309/20 (2013.01); C07D 317/28 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 403/04 (2013.01); C07D 403/06 (2013.01); C07D 403/10 (2013.01); C07D 405/04 (2013.01); C07D 417/06 (2013.01); C07B 2200/07 (2013.01); C07C 2601/02 (2017.05); C07C 2601/04 (2017.05); C07C 2601/14 (2017.05); C07C 2602/44 (2017.05);
Abstract

Provided are novel compounds of Formula (I): and pharmaceutically acceptable salts thereof, which are useful for treating a variety of diseases, disorders or conditions, associated with LSD1. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I), pharmaceutically acceptable salts thereof, and methods for their use in treating one or more diseases, disorders or conditions, associated with LSD1.


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