The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2020
Filed:
Jul. 06, 2016
Base4 Innovation Ltd, Cambridge, Cambridgeshire, GB;
Cameron Alexander Frayling, Cambridge, GB;
Thomas Henry Isaac, Cambridge, GB;
BASE4 INNOVATION LTD, Cambridge, Cambridgeshire, GB;
Abstract
An apparatus for sequencing a nucleic acid by printing droplets at least some of which contain single nucleotides derived from the nucleic acid is provided. It is characterised by comprising; •a planar substrate having a face with droplet-receiving locations arranged in at least one track parallel to a first axis defining the substrate; ⋅a printer head comprising a plurality of droplet-dispensing nozzle groups juxtaposed above the droplet-receiving locations so that each nozzle group can in turn dispense a droplet into the droplet-receiving locations; •a means for stepping the printer head along the first axis relative to the droplet-receiving locations; ⋅a nucleotide-generating site upstream of the printer head by means of which an ordered stream of single nucleotides is created from the nucleic acid and delivered to a first droplet-dispensing nozzle group; •at least one source of incident electromagnetic radiation adapted to illuminate the droplet-receiving locations and ⋅at least one photodetector to detect adapted to detect fluorescence radiation emitted by each droplet-receiving location after illumination.