The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2020

Filed:

Dec. 12, 2007
Applicants:

Ofer Toledano, Kfar Saba, IL;

Hanan Sertchook, Gedera, IL;

Raed Abu-reziq, Jatt Hamesholash, IL;

Haim Bar-simantov, Modiin, IL;

Leora Shapiro, Jerusalem, IL;

Inventors:

Ofer Toledano, Kfar Saba, IL;

Hanan Sertchook, Gedera, IL;

Raed Abu-Reziq, Jatt Hamesholash, IL;

Haim Bar-Simantov, Modiin, IL;

Leora Shapiro, Jerusalem, IL;

Assignee:

SOL-GEL TECHNOLOGIES LTD., Ness Ziona, IL;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/66 (2006.01); A61K 8/06 (2006.01); A61K 8/18 (2006.01); A61Q 11/00 (2006.01); A61Q 17/04 (2006.01); B01J 13/14 (2006.01);
U.S. Cl.
CPC ...
B01J 13/14 (2013.01);
Abstract

A process for preparing nanocapsules having a core-shell structure, comprising: (a) preparing an oil-in-water emulsion by emulsification of an oily phase that comprises a core material, in an aqueous phase, under high shear forces, wherein one or both of the oily phase, and the aqueous phase comprises a sol-gel precursor; (b) subjecting the emulsion obtained in (a) to a high pressure homogenization to obtain a nano-emulsion; and (c) applying conditions for hydrolyzing and polycondensing the sol-gel precursor to obtain nanocapsules having a metal oxide shell encapsulating the core material, said nanocapsules have a particle size distribution of: d10=10-80 nm, d50=30-200 nm, and d90=70-500 nm, in diameter. The invention also relate to nanocapsules having the above particle size distribution and to composition comprising the nanocapsules.


Find Patent Forward Citations

Loading…