The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2020

Filed:

Nov. 06, 2015
Applicant:

The Asan Foundation, Seoul, KR;

Inventors:

Sang-ju Lee, Seoul, KR;

Seung-jun Oh, Seoul, KR;

Dae-hyuk Moon, Seoul, KR;

Jin-sook Ryu, Seoul, KR;

Jae-seung Kim, Seoul, KR;

Jong-jin Lee, Seoul, KR;

Assignee:

THE ASAN FOUNDATION, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/04 (2006.01); A61K 51/02 (2006.01); C07C 17/38 (2006.01); C07C 17/383 (2006.01); C07C 17/389 (2006.01); C07C 19/08 (2006.01); C07C 21/18 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
A61K 51/04 (2013.01); A61K 51/02 (2013.01); C07B 59/00 (2013.01); C07C 17/38 (2013.01); C07C 17/383 (2013.01); C07C 17/389 (2013.01); C07C 19/08 (2013.01); C07C 21/18 (2013.01);
Abstract

A method for preparing a radiopharmaceutical and, specifically, a method for preparing an organic fluoride-aliphatic compound usable as a radiopharmaceutical, a method for purifying the prepared organic fluoride-aliphatic compound, and a method for preparing a radiopharmaceutical by using a cassette comprising a backdraft preventing reaction container. A method for preparing an organic fluorinated aliphatic compound includes allowing a fluorine salt to react with a leaving group-containing aliphatic compound by using a multifunctional solvent represented by the following Chemical Formula 1 to obtain an aliphatic compound labeled with [F] fluoride substituting for the leaving group. The organic fluoride-aliphatic compound can be prepared and purified through even a simple process at high yield, high efficiency, and high purity, and the radiopharmaceutical can be safely prepared without damage to a synthetic apparatus.


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