The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2020
Filed:
Jan. 26, 2017
Applicant:
Sanofi, Paris, FR;
Inventors:
Julia Schnieders, Frankfurt, DE;
Dirk Usener, Frankfurt, DE;
Sabrina Ruggeberg, Frankfurt, DE;
Ahmed Youssef, Frankfurt, DE;
Martina Kirsch, Frankfurt, DE;
Annika Hagendorf, Hattersheim, DE;
Assignee:
Sanofi, Paris, FR;
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 9/19 (2006.01); A61K 47/12 (2006.01); A61K 47/22 (2006.01); A61K 47/26 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39591 (2013.01); A61K 9/19 (2013.01); A61K 39/3955 (2013.01); A61K 39/39558 (2013.01); A61K 47/12 (2013.01); A61K 47/22 (2013.01); A61K 47/26 (2013.01); C07K 16/2866 (2013.01); C07K 16/2875 (2013.01); C07K 2317/21 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/52 (2013.01); C07K 2317/565 (2013.01);
Abstract
The present invention provides stable pharmaceutical antibody formulations, including liquid drug product formulations and lyophilized drug product formulations, comprising an IgG4 binding agent and a citrate buffer, wherein the pH of the formulation is at or below both pH 6 and the pI of the binding agent. The formulations can be used in the treatment of chronic bowel diseases or rheumatoid arthritis.