The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2020

Filed:

Aug. 22, 2017
Applicant:

Ansun Biopharma, Inc., San Diego, CA (US);

Inventors:

Fang Fang, San Diego, CA (US);

Michael P. Malakhov, San Diego, CA (US);

Assignee:

Ansun Biopharma, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 38/47 (2006.01); C12N 9/24 (2006.01); C07K 14/47 (2006.01); C07K 14/52 (2006.01); C07K 14/54 (2006.01); C07K 14/775 (2006.01); C07K 14/81 (2006.01); A61K 48/00 (2006.01); C12N 7/00 (2006.01); C12N 15/86 (2006.01); C07K 14/475 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/47 (2013.01); A61K 48/0008 (2013.01); C07K 14/47 (2013.01); C07K 14/4703 (2013.01); C07K 14/475 (2013.01); C07K 14/4711 (2013.01); C07K 14/521 (2013.01); C07K 14/522 (2013.01); C07K 14/5421 (2013.01); C07K 14/775 (2013.01); C07K 14/8117 (2013.01); C07K 14/8128 (2013.01); C12N 7/00 (2013.01); C12N 9/2402 (2013.01); C12N 9/2405 (2013.01); C12N 15/86 (2013.01); C12Y 302/01018 (2013.01); A61K 38/00 (2013.01); A61K 39/00 (2013.01); C07K 2319/00 (2013.01); C07K 2319/01 (2013.01); C07K 2319/33 (2013.01); C12N 2750/14143 (2013.01); C12N 2750/14145 (2013.01); C12N 2760/16111 (2013.01);
Abstract

The present invention provides new compositions and methods for preventing and treating pathogen infection. In particular, the present invention provides compounds having an anchoring domain that anchors the compound to the surface of a target cell, and a therapeutic domain that can act extracellularly to prevent infection of a target cell by a pathogen, such as a virus. The present invention also comprises therapeutic compositions having sialidase activity, including protein-based compounds having sialidase catalytic domains. Compounds of the invention can be used for treating or preventing pathogen infection, and for treating and reducing allergic and inflammatory responses. The invention also provides compositions and methods for enhancing transduction of target cells by recombinant viruses. Such compositions and methods can be used in gene therapy.


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