The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2020
Filed:
Dec. 08, 2017
Applicant:
Rosalind Franklin University of Medicine and Science, North Chicago, IL (US);
Inventor:
Michelle L. Hastings, North Chicago, IL (US);
Assignee:
Rosalind Franklin University of Medicine and Science, North Chicago, IL (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/712 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 31/712 (2013.01); C12N 15/1138 (2013.01); A01K 2267/0306 (2013.01); C12N 2310/11 (2013.01); C12N 2310/321 (2013.01); C12N 2310/3233 (2013.01); C12N 2320/33 (2013.01);
Abstract
The present disclosure relates generally to compounds comprising oligonucleotides complementary to a cystic fibrosis transmembrane conductance regulator (CFTR) RNA transcript. Certain such compounds are useful for hybridizing to a CFTR RNA transcript, including but not limited to a CFTR RNA transcript in a cell. In certain embodiments, such hybridization results in modulation of splicing of the CFTR transcript. In certain embodiments, such compounds are used to treat one or more symptoms associated with Cystic Fibrosis.